Dr. Matthew Shane received his PhD in Psychology from the University of Toronto in 2004. Following post-doctoral positions at University of Wisconsin—Madison and Yale University, he accepted the position of Assistant Professor of Translational Neuroscience at The Mind Research Network (MRN) in Albuquerque, New Mexico. After five years at MRN, he joined the faculty at Ontario Tech University. He now holds joint positions at both institutions. His research program focuses primarily on understanding the cognitive and emotional processes underlying the antisocial personality and its related disorders (e.g., substance abuse). He is particularly interested in psychopathic individuals, who are believed to experience significantly less intense negative emotions, including fear, guilt and shame, than the average person. He primarily utilizes cognitive neuroscience methodologies to better understand the nature of these emotional reductions, and the neural systems underlying these reductions. Current research focuses on evaluating whether these individuals are truly incapable of experiencing normal levels of these negative emotions. Longer-term goals focus on the development of novel treatment protocols for severely antisocial individuals. Dr. Shane has been fortunate enough to have received generous support for his work from several funding agencies, including the National Institute of Health (NIH). He is currently administering a five-year $1.8-million NIH-supported project focused on investigating the extent to which antisocial substance abusers show abnormalities in their neural responses to negative feedback. Previous NIH-funded projects have focused on evaluating emotional processing in psychopathic individuals, and the ability of substance abusers to alter their brain’s craving response to their drugs of abuse. Additional work in the lab is using cognitive and neuroscience methods to evaluate antisocial individuals’ abilities to learn from their mistakes, control their own emotional responses and avoid abusing illegal substances.